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Marc Andreessen: Ethereum and Web3 Lead Bitcoin on Tech Innovation

Reported by Blockworks
Mar 10, 2026· 2 min read
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Key Takeaways
  • • Marc Andreessen has shifted his investment thesis away from Bitcoin as the primary innovation driver, now positioning Ethereum and Web3 as the core technological transformations in blockchain, citing Bitcoin's stalled evolution since his 2014 prediction.
  • • Andreessen Horowitz maintains substantial exposure to the crypto ecosystem through its $4.5 billion crypto fund launched in 2022—the largest crypto-venture fund ever—alongside its 2018 flagship crypto fund, despite that fund experiencing a 40% loss in the first half of 2022.
  • • A16Z's current crypto portfolio includes major holdings in Alchemy, Aptos, Avalanche, Chia, Compound, Coinbase, Lido, Mysten Labs, and Yuga Labs, demonstrating continued conviction in blockchain infrastructure and application layer projects beyond Bitcoin.
  • • Andreessen characterizes Web3 as completing the internet's original vision by enabling business transactions, money movement, and trust mechanisms that were technologically impossible during the 1990s internet build-out, positioning blockchain as solving a fundamental architectural gap.
Summary
Marc Andreessen, the legendary technologist and co-founder of Andreessen Horowitz, has publicly revised his long-standing thesis on Bitcoin's role in crypto innovation. In a Wednesday interview with Reason Magazine, Andreessen acknowledged that his 2014 prediction—that Bitcoin would become as transformative as the internet itself—has not materialized as expected. He attributed this shortfall to Bitcoin's limited evolution, stating it "basically stopped evolving" into the multi-application platform he once envisioned.

Rather than abandoning the crypto sector entirely, Andreessen has reoriented his conviction toward Ethereum and Web3 as the primary engines of blockchain-driven transformation. "I would either say Ethereum instead of Bitcoin, or I would just say crypto or Web3 instead of Bitcoin," he stated. This recalibration reflects a broader shift in a16z's investment strategy, though the firm has maintained substantial capital deployment in the crypto ecosystem through its $4.5 billion dedicated crypto fund, launched in 2022 as the largest crypto-venture fund to date.

Andreessen's rationale centers on Web3's capacity to address gaps in the original internet architecture. According to his analysis, Web3 incorporates all the transactional, monetary, and trust-based features that internet pioneers recognized as necessary but lacked the technological means to implement during the 1990s. "We did not know how to use the internet to do that in the 90s. And now, with this technological breakthrough of the blockchain, we now know how to do that, we have the technological foundation to be able to do that," he explained.

A16Z's portfolio positioning underscores this thesis. The firm's crypto investments span infrastructure (Alchemy, Aptos, Avalanche), applications (Compound, Lido), platforms (Coinbase), and entertainment (Yuga Labs). While a16z's flagship 2018 crypto fund experienced a 40% loss in the first half of 2022, the firm's willingness to deploy the $4.5 billion fund signals continued conviction in blockchain's longer-term potential despite near-term volatility and market headwinds.

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Sources

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Blockworks Marc Andreessen: Ethereum and Web3 Lead Bitcoin on Tech Innovation